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1

2- and 3-[(Aryl)(azolyl)methyl]indoles as Potential Non-steroidal Aromatase Inhibitors

Lézé, Marie-Pierre, Borgne, Marc Le, Marchand, Pascal, Loquet, Denis, Kogler, Manuela, Baut, Guillaume Le, Palusczak, Anja, Hartmann, Rolf W.

Journal:

Journal of Enzyme Inhibition and Medicinal Chemistry

Year:

2004

Language:

english

File:

PDF, 193 KB

english, 2004

2

ChemInform Abstract: SYNTHESE N-SUBSTITUIERTER PYROPHTHALONE DURCH KONDENSATION VON PYRIDINIUMSALZEN MIT INDANDION-(1,3)

PLOQUIN, JEAN, SPARFEL, LOUIS, LE BAUT, GUILLAUME, FLOC'H, ROBERT

Journal:

Chemischer Informationsdienst

Year:

1975

File:

PDF, 114 KB

1975

3

Synthesis and biological evaluation of 3-(azolylmethyl)-1 H -indoles and 3-(α-azolylbenzyl)-1 H -indoles as selective aromatase inhibitors

BORGNE, MARC LE, MARCHAND, PASCAL, NOURRISSON, MARIE-RENEE, LOQUET, DENIS, PALZER, MARTINA, LE BAUT, GUILLAUME, HARTMANN, ROLF W.

Journal:

Journal of Enzyme Inhibition and Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 244 KB

english, 2007

4

New N -Pyridinyl(methyl)-N1-substituted-3-indolepropanamides Acting as Topical and Systemic Anti-inflammatory Agents

Gallard, Anthony, Duflos, Muriel, Nourrisson, Marie-Renee, Le Baut, Guillaume, Grimaud, Nicole, Petit, Jean Yves

Journal:

Journal of Enzyme Inhibition and Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 436 KB

english, 2003

5

ChemInform Abstract: Synthesis and Antileishmanial Activity of New 1-(Pyridin-2-yl)imidazolidin-2-ones Derived from 2-Amino-4,6-dimethylpyridine.

Hiam Abdala, Jean-Michel Robert, Patrice Le Pape, Gaetane Wielgosz, Sylvie Robert-Piessard, Guillaume Le Baut

Journal:

Year:

2000

File:

PDF, 30 KB

2000

6

ChemInform Abstract: New Antiinflammatory N-Pyridinyl(alkyl)phthalimides Acting as Tumor Necrosis Factor-α Production Inhibitors.

Xavier Collin, Jean-Michel Robert, Gaetane Wielgosz, Guillaume Le Baut, Christine Bobin-Dubigeon, Nicole Grimaud, Jean-Yves Petit

Journal:

Year:

2002

File:

PDF, 33 KB

2002

7

New anti-inflammatory N-pyridinyl(alkyl)phthalimides acting as tumour necrosis factor-α production inhibitors

Xavier Collin, Jean-Michel Robert, Gaétane Wielgosz, Guillaume Le Baut, Christine Bobin-Dubigeon, Nicole Grimaud, Jean-Yves Petit

Journal:

European Journal of Medicinal Chemistry

Year:

2001

Language:

english

File:

PDF, 198 KB

english, 2001

8

New N -(Pyridin-4-yl)-(indol-3-yl)acetamides and Propanamides as Antiallergic Agents

Menciu, Cecilia, Duflos, Muriel, Fouchard, Fabienne, Le Baut, Guillaume, Emig, Peter, Achterrath, Ute, Szelenyi, Istvan, Nickel, Bernd, Schmidt, Jürgen, Kutscher, Bernhard, Günther, Eckhardt

Journal:

Journal of Medicinal Chemistry

Year:

1999

Language:

english

File:

PDF, 175 KB

english, 1999

9

Oxaliplatin-induced bronchiolitis obliterans organizing pneumonia following hyperthermic intraperitoneal chemotherapy

Le Baut, Guillaume, Guilloit, Jean-Marc, Leprince, Vincent, Ollivier, Yann, Dubos-Arvis, Catherine, Do, Pascal, Sutter, Jasmine, Loge, Ludovic, Gervais, Radj

Journal:

Journal of gastrointestinal oncology

Year:

2018

Language:

english

File:

PDF, 1013 KB

english, 2018

10

ChemInform Abstract: Synthesis and Pharmacological Evaluation of New (Indol-3-yl)alkylamides and Alkylamines Acting as Potential Serotonin Uptake Inhibitors.

Fabienne Fouchard, Cecilia Menciu, Muriel Duflos, Guillaume Le Baut, Bernard Lambrey, Marie Mourgues, Daniel Perrissoud

Journal:

Year:

1999

Language:

english

File:

PDF, 32 KB

english, 1999

11

Synthesis and biological evaluation of 5-[(aryl)(1H-imidazol-1-yl)methyl]-1H-indoles: Potent and selective aromatase inhibitors

Marie-Pierre Lézé, Marc Le Borgne, Patricia Pinson, Anja Palusczak, Muriel Duflos, Guillaume Le Baut, Rolf W. Hartmann

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 123 KB

english, 2006

12

ChemInform Abstract: EINFLUSS DER DIMERISIERUNG AUF DIE VERTEILUNGSKOEFFIZIENTEN VON GAMMA-PYROPHTHALONEN

PLOQUIN, JEAN, SPARFEL, LOIC, LE BAUT, GUILLAUME

Journal:

Chemischer Informationsdienst

Year:

1973

File:

PDF, 119 KB

1973

13

New N -pyridinyl(methyl)-indole-2- and 3-(Alkyl)carboxamides and Derivatives Acting as Systemic and Topical Inflammation Inhibitors

Breteche, Anne, Duflos, Muriel, Dassonville, Alexandra, Nourrisson, Marie-Renee, Brelet, Jacques, Le Baut, Guillaume, Grimaud, Nicole, Petit, Jean-Yves

Journal:

Journal of Enzyme Inhibition and Medicinal Chemistry

Year:

2002

Language:

english

File:

PDF, 269 KB

english, 2002

14

Retinoic Acid Metabolism Inhibition by 3-Azolylmethyl-1 H -indoles and 2, 3 or 5-(α-Azolylbenzyl)-1 H -indoles

Le Borgne, Marc, Marchand, Pascal, Le Baut, Guillaume, Ahmadi, Masoud, John Smith, H., Nicholls, Paul J.

Journal:

Journal of Enzyme Inhibition and Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 145 KB

english, 2003

15

Potential Inhibitors of Angiogenesis. Part II: 3-(Azolylmethylene)-2,3-dihydrobenzo[<emph type="2">b</emph>]furan-2-ones

Braud, Emmanuelle, Duflos, Muriel, Le Baut, Guillaume, Renard, Pierre, Pfeiffer, Bruno, Tucker, Gordon

Journal:

Journal of Enzyme Inhibition and Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 170 KB

english, 2003

16

New selective nonsteroidal aromatase inhibitors: Synthesis and inhibitory activity of 2,3 or 5-(α-azolylbenzyl)-1H-indoles

Marc Le Borgne, Pascal Marchand, Bénédicte Delevoye-Seiller, Jean-Michel Robert, Guillaume Le Baut, Rolf W. Hartmann, Martina Palzer

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1999

Language:

english

File:

PDF, 253 KB

english, 1999

17

Inhibition of Parasite Protein Kinase C by New Antileishmanial Imidazolidin-2-one Compounds

Alvarez, Nidia, Robledo, Sara, Velez, Ivan Dario, Robert, Jean Michel, Baut, Guillaume Le, Pape, Patrice Le

Journal:

Journal of Enzyme Inhibition and Medicinal Chemistry

Year:

2002

Language:

english

File:

PDF, 182 KB

english, 2002

18

Synthesis and Antileishmanial Activity of 3-Imidazolylalkylindoles. Part I

Min Na, Young, Lebouvier, Nicolas, Borgne, Marc Le, Pagniez, Fabrice, Alvarez, Nidia, Le Pape, Patrice, Le Baut, Guillaume

Journal:

Journal of Enzyme Inhibition and Medicinal Chemistry

Year:

2004

Language:

english

File:

PDF, 160 KB

english, 2004

19

Prevalence of Yersinia Species in the Ileum of Crohn's Disease Patients and Controls

Le Baut, Guillaume, O'Brien, Claire, Pavli, Paul, Roy, Maryline, Seksik, Philippe, Tréton, Xavier, Nancey, Stéphane, Barnich, Nicolas, Bezault, Madeleine, Auzolle, Claire, Cazals-Hatem, Dominique, Via

Journal:

Frontiers in Cellular and Infection Microbiology

Year:

2018

Language:

english

File:

PDF, 1.73 MB

english, 2018

20

ChemInform Abstract: REAKTIVITAET DER METHYLGRUPPEN BEI DER KONDENSATION VON 2,4-LUTIDIN UND 2,4,6-COLLIDIN MIT PHTHALSAEUREANHYDRID

PLOQUIN, JEAN, SPARFEL, LOUIS, LE BAUT, GUILLAUME, FLOC'H, ROBERT

Journal:

Chemischer Informationsdienst

Year:

1975

File:

PDF, 214 KB

1975

21

Synthesis and In Vitro Evaluation of 3-(1-Azolylmethyl)-1H-indoles and 3-(1-Azolyl-1-phenylmethyl)-1H-indoles as Inhibitors of P450 arom

Marc Le Borgne, Pascal Marchand, Muriel Duflos, Bénédicte Delevoye-Seiller, Sylvie Piessard-Robert, Guillaume Le Baut, Rolf W. Hartmann, M. Palzer

Journal:

Archiv der Pharmazie

Year:

1997

Language:

english

File:

PDF, 500 KB

english, 1997

22

Palladium(II)-catalyzed heterocyclisation of 8-arylethynyl-1,2,3,4-tetrahydroquinolines: a facile route to 2-aryl-5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinoline derivatives

Pascal Marchand, Alain Puget, Guillaume Le Baut, Peter Emig, Michael Czech, Eckhard Günther

Journal:

Year:

2005

Language:

english

File:

PDF, 175 KB

english, 2005

23

Synthesis of new bifunctional chelating agents: (1R,2R,4S)-4-isothiocyanatocyclohexane-1,2-diamine-N,N,N′,N′-tetrakismethanephosphonic acid (4-ICMP) and (1R,2R,4S)-4-isothiocyanatocyclohexane-1,2-diamine-N,N,N′,N′-tetrakisethanephosphonic acid (4-ICEP)

Loussouarn, Anthony, Duflos, Muriel, Benoist, Eric, Chatal, Jean-François, Le Baut, Guillaume, Gestin, Jean-François

Journal:

Journal of the Chemical Society Perkin Transactions 1

Year:

1998

Language:

english

File:

PDF, 103 KB

english, 1998

24

Synthesis and Antifungal Activity of New 1-Halogenobenzyl-3-imidazolylmethylindole Derivatives.

Young-Min Na, Marc Le Borgne, Fabrice Pagniez, Guillaume Le Baut, Patrice Le Pape

Journal:

Year:

2003

File:

PDF, 95 KB

2003

25

Mo1899 – Prognostic Factors for Long-Term Adalimumab Treatment in Crohn’s Disease : A Multicenter Experience

Pariente, Benjamin, Duveau, Nicolas, Perignon, Claire-Anne, Lepeut, Gabriel, Lahaye, Anouck, baut, Guillaume le, Rouillon, Clea, Yzet, Clara, Loreau, Julien, Wils, Pauline, Nachury, Maria, Fumery, Mat

Journal:

Gastroenterology

Year:

2019

Language:

english

File:

PDF, 90 KB

english, 2019

26

New N-Pyridinyl(methyl)-indolalkanamides Acting as Topical Inflammation Inhibitors.

Alexandra Dassonville, Anne Breteche, Johan Evano, Muriel Duflos, Guillaume le Baut, Nicole Grimaud, Jean-Yves Petit

Journal:

Year:

2005

File:

PDF, 14 KB

2005

27

New N-pyridinyl(methyl)-indolalkanamides acting as topical inflammation inhibitors

Alexandra Dassonville, Anne Bretéché, Johan Evano, Muriel Duflos, Guillaume le Baut, Nicole Grimaud, Jean-Yves Petit

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 267 KB

english, 2004

28

Proceedings of the 16th annual conference of the Groupement des Pharmacochimistes de l'Arc Atlantique (GP2A)

Guillon, Jean, Le Baut, Guillaume, Le Borgne, Marc

Journal:

Journal of Enzyme Inhibition and Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 33 KB

english, 2008

29

Synthesis of 1-Benzyl-8,9-dihydroimidazo[4,5-c]pyrrolo[3,2-g]quinolin-4(5H)-one via Palladium-Catalyzed Intramolecular Arylation.

Bruno Delest, Jean-Yves Tisserand, Jean-Michel Robert, Marie-Renee Nourisson, Patricia Pinson, Muriel Duflos, Guillaume Le Baut, Pierre Renard, Bruno Pfeiffer

Journal:

Year:

2004

File:

PDF, 22 KB

2004

30

Synthesis and Central Dopaminergic Effects of N-(4,6-Dimethyl-2-pyridinyl)benzamides

Bouhayat, Saïd, Piessard, Sylvie, Baut, Guillaume Le, Sparfel, Louis, Petit, Jean-Yves, Piriou, François, Welin, Lucien

Journal:

Journal of Medicinal Chemistry

Year:

1985

Language:

english

File:

PDF, 728 KB

english, 1985

31

In Vitro Activity of a New Antifungal Azolyl-substituted Indole Against Aspergillus fumigatus

Pagniez, Fabrice, Le Borgne, Marc, Marchand, Pascal, Min Na, Young, Le Baut, Guillaume, Robert-Piessard, Sylvie, Le Pape, Patrice

Journal:

Journal of Enzyme Inhibition and Medicinal Chemistry

Year:

2002

Language:

english

File:

PDF, 145 KB

english, 2002

32

Antileishmanial activities and mechanisms of action of indole-based azoles

Pagniez, Fabrice, Abdala-Valencia, Hiam, Marchand, Pascal, Le Borgne, Marc, Le Baut, Guillaume, Robert-Piessard, Sylvie, Le Pape, Patrice

Journal:

Journal of Enzyme Inhibition and Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 173 KB

english, 2006

33

Preparation and Pharmacological Profile of 7-(α-Azolylbenzyl)-1H-indoles and Indolines as New Aromatase Inhibitors.

Pascal Marchand, Marc Le Borgne, Martina Palzer, Guillaume Le Baut, Rolf W. Hartmann

Journal:

Year:

2003

File:

PDF, 137 KB

2003

34

Potential application of plant lipid transfer proteins for drug delivery

Christine Pato, Marc Le Borgne, Guillaume Le Baut, Patrice Le Pape, Didier Marion, Jean-Paul Douliez

Journal:

Biochemical Pharmacology

Year:

2001

Language:

english

File:

PDF, 260 KB

english, 2001

35

Medicinal Chemistry and the Pharmacochemistry Grouping of the Atlantic Arc

Guillaume Le Baut

Journal:

Journal of Pharmacy and Pharmacology

Year:

1997

Language:

english

File:

PDF, 112 KB

english, 1997

36

8-Amino-5-nitro-6-phenoxyquinolines: Potential Non-peptidic Neuropeptide Y Receptor Ligands

Wielgosz-collin, Gaetane, Duflos, Muriel, Pinson, Patricia, Le baut, Guillaume, Renard, Pierre, Bennejean, Caroline, Boutin, Jean, Boulanger, Michele

Journal:

Journal of Enzyme Inhibition and Medicinal Chemistry

Year:

2002

Language:

english

File:

PDF, 153 KB

english, 2002

37

Indanediones-1,3 VIII. Hydroxy-2 indolyl-2 indanediones-1,3, (indolyl-3 méthylène)-2 indanediones-1,3 et dérivés: recherche d'une activité anti-inflammatoire

Jacqueline Courant, Danielle Leblois, Manju Tandon, Sylvie Robert-Piessard, Guillaume Le Baut, Marcel Juge, Jean-Yves Petit, Lucien Welin

Journal:

European Journal of Medicinal Chemistry

Year:

1989

File:

PDF, 890 KB

1989

38

6-Amino-2,4-lutidine carboxamides: α-aminoamide derivatives as systemic and topical inflammation inhibitors

Muriel Duflos, Jacqueline Courant, Guillaume Le Baut, Nicole Grimaud, Pierre Renard, Dominique Manechez, Daniel-Henri Caignard

Journal:

European Journal of Medicinal Chemistry

Year:

1998

Language:

english

File:

PDF, 1.02 MB

english, 1998

39

ChemInform Abstract: New Selective Nonsteroidal Aromatase Inhibitors: Synthesis and Inhibitory Activity of 2, 3, or 5-(α-Azolylbenzyl)-1H-indoles.

Marc Le Borgne, Pascal Marchand, Benedicte Delevoye-Seiller, Jean-Michel Robert, Guillaume Le Baut, Rolf W. Hartmann, Martina Palzer

Journal:

Year:

1999

File:

PDF, 32 KB

1999

40

Efficient microwave-assisted synthesis of 1-(1H-indol-1-yl)-2-phenyl-3-(1H-1,2,4-triazol-1-yl)propan-2-ols as antifungal agents

Nicolas Lebouvier, Francis Giraud, Typhanie Corbin, Young Min Na, Guillaume Le Baut, Pascal Marchand, Marc Le Borgne

Journal:

Tetrahedron Letters

Year:

2006

Language:

english

File:

PDF, 104 KB

english, 2006

41

N -Pyridinyl(methyl)-indole-1- or 3-propanamides and propenamides acting as topical and systemic inflammation inhibitors

Dassonville, Alexandra, Lardic, Morgane, Breteche, Anne, Nourrisson, Marie Renee, Le Baut, Guillaume, Grimaud, Nicole, Petit, Jean-Yves, Duflos, Muriel

Journal:

Journal of Enzyme Inhibition and Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 244 KB

english, 2008

42

Pyrophtalones VII. Synthèse et activité anti-inflammatoire de (pyridinyl-4)-2 indanediones-1,3 substituées sur le noyau benzénique et/ou sur l'hétérocycle

Danielle Leblois, Sylvie Piessard, Guillaume Le Baut, Piyush Kumar, Jean-Daniel Brion, Louis Sparfel, René-Yann Sanchez, Marcel Juge, Jean-Yves Petit, Lucien Welin

Journal:

European Journal of Medicinal Chemistry

Year:

1987

File:

PDF, 1.21 MB

1987

43

Synthesis and anti-inflammatory activity of N-(aza)arylcarboxamides derived from Trolox®

Claudie Moulin, Muriel Duflos, Guillaume Le Baut, Nicole Grimaud, Pierre Renard, Daniel-Henri Caignard

Journal:

European Journal of Medicinal Chemistry

Year:

1998

Language:

english

File:

PDF, 638 KB

english, 1998

44

Synthesis of 1-benzyl-8,9-dihydroimidazo[4,5-c]pyrrolo[3,2-g]quinolin-4(5H)-one via palladium-catalyzed intramolecular arylation

Bruno Delest, Jean-Yves Tisserand, Jean-Michel Robert, Marie-Renée Nourrisson, Patricia Pinson, Muriel Duflos, Guillaume Le Baut, Pierre Renard, Bruno Pfeiffer

Journal:

Year:

2004

Language:

english

File:

PDF, 161 KB

english, 2004

45

Synthesis and antifungal activity of new 1-halogenobenzyl-3-imidazolylmethylindole derivatives

Young-Min Na, Marc Le Borgne, Fabrice Pagniez, Guillaume Le Baut, Patrice Le Pape

Journal:

European Journal of Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 245 KB

english, 2003

46

Synthesis and antileishmanial activity of new imidazolidin-2-one derivatives

Jean-Michel H Robert, Caroline Sabourin, Nidia Alvarez, Sylvie Robert-Piessard, Guillaume Le Baut, Patrice Le Pape

Journal:

European Journal of Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 493 KB

english, 2003

47

ChemInform Abstract: ELEKTRONENSPEKTREN UND STRUKTUR VON PYROPHTHALONEN

AMIEL, JEAN, PLOQUIN, JEAN, SPARFEL, LOUIS, LE BAUT, GUILLAUME, FLOC'H, ROBERT

Journal:

Chemischer Informationsdienst

Year:

1975

File:

PDF, 88 KB

1975

48

ChemInform Abstract: Synthesis and Pharmacological Evaluation of (Indol-3-yl)alkylamides as Potent Analgesic Agents.

Fabienne Fouchard, Pascal Marchand, Guillaume Le Baut, Peter Emig, Bernd Nickel

Journal:

Year:

2002

File:

PDF, 26 KB

2002

49

Synthesis and structure–activity relationships of N-aryl(indol-3-yl)glyoxamides as antitumor agents

Pascal Marchand, Maud Antoine, Guillaume Le Baut, Michael Czech, Silke Baasner, Eckhard Günther

Journal:

Bioorganic & Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 2.66 MB

english, 2009

50

Synthesis and antifungal activities of new fluconazole analogues with azaheterocycle moiety

Nicolas Lebouvier, Fabrice Pagniez, Muriel Duflos, Patrice Le Pape, Young Min Na, Guillaume Le Baut, Marc Le Borgne

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2007

Language:

english

File:

PDF, 132 KB

english, 2007

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